Since its inception in 2004, LASER has featured the following speakers:
- 2018 – Software Technology for Blockchains, Bitcoin and Distributed Trust Systems Christian Cachin, Primavera De Filippi, Maurice Herlihy, Christoph Jentzsch, Bertrand Meyer, Emin Gun Sirer, Roger Wattenhofer, Dominic Woerner
- 2017 – Software for Robotics Davide Brugali, Rudolphe Gelin, Ashish Kapoor, Nenad Medvidovic, Bertrand Meyer, Issa Nesnas, Hiroshi “Gitchang” Okuno
- 2015 – Concurrency: the Next Frontiers Manfred Broy, Maurice Herlihy, Jeff Kramer, Jayadev Misra, David Parnas, Bertrand Meyer
- 2014 – Leading-Edge Software Engineering Harald C. Gall, Daniel Jackson, Michael Jackson, Erik Meijer, Gail C. Murphy, Moshe Y. Vardi, Judith Bishop, Bertrand Meyer
- 2013 – Software for the Cloud and Big Data Roger Barga, Karin Breitman, Sebastian Burckhardt, Adrian Cockcroft, Carlo Ghezzi, Anthony Joseph, Pere Mato Vila, Bertrand Meyer
- 2012 – Innovative Languages for Software Engineering Andrei Alexandrescu, Roberto Ierusalimschy, Ivar Jacobson, Erik Meijer, Bertrand Meyer, Martin Odersky, Simon Peyton-Jones, Guido van Rossum
- 2011 – Tools for Practical Software Verification Edmund Clarke, Patrick Cousot, Patrice Godefroid, Rustan Leino, Bertrand Meyer, César Muñoz, Christine Paulin-Mohring, Andrei Voronkov
- 2010 – Empirical Software Engineering Victor Basili, Joshua Bloch, Barry Boehm, Natalia Juristo, Tim Menzies, Bertrand Meyer, Walter F. Tichy
- 2009 – Software Testing: The Practice And The Science Alberto Avritzer, Michel Cukier, Yuri Gurevich, Mark Harman, Bertrand Meyer, Tom Ostrand, Mauro Pezzè, Elaine Weyuker
- 2008 – Concurrency and Correctness Tryggve Fossum, Maurice Herlihy, C.A.R Hoare, Bertrand Meyer, Robin Milner, Peter O’Hearn, Daniel A. Reed
- 2007 – Applied Software Verification Thomas Ball, Gérard Berry, C.A.R Hoare, Bertrand Meyer, Peter Müller, Natarajan Shankar
- 2006 – Practical Programming Processes Ralph-Johan Back, Miguel de Icaza, Erik Meijer, Bertrand Meyer, Mary Poppendieck, Andreas Zeller
- 2005 – Software engineering for concurrent and real-time systems Laura K. Dillon, Bertrand Meyer, Jayadev Misra, Amir Pnueli, Wolfgang Pree, Joseph Sifakis
- 2004 – Practical Techniques of Software Quality Jean-Raymond Abrial, Ernie Cohen, Erich Gamma, Bertrand Meyer, Carroll Morgan, Pamela Zave